Tocilizumab : Repurposing candidate for treatment of Cytokine Release Syndrome caused by SARS-CoV-2 infection.

Cytokine storm is an uncontrolled release of cytokines in the body in response to external stimuli leading to systemic inflammation. Ferrara et al. (1993) first coined the term “cytokine storm” in graft-versus-host disease. Approximately, 15.7% of COVID-19 patients develop severe pneumonia and...

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Neutralizing Antibodies - An approach for COVID-19 treatment?

Immune or "convalescent” plasma refers to plasma collected from infected individuals, post resolution of infection. These infected individuals develop antibodies against the infection. Passive antibody administration through transfusion of convalescent plasma may offer a short-term strategy to...

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GOBIOM - Understanding the platform's utility in clinical research and drug development

GOBIOM (Global Online Biomarker Database) is the world’s largest manually curated database of validated and putative biomarkers, providing critical insights into the relationship between biomarker and disease. GOBIOM as a one-stop platform provides clinical and pre-clinical information on...

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Immunostimulation - A key driver to combat coronavirus

Although three human coronaviruses namely: SARS-CoV, MERS-CoV, and SARS-CoV-2 have hit mankind in last two decades, no vaccines have yet been developed against them. Vaccines are the most effective strategy for preventing infectious disease including viral diseases like COVID-19. Specialized...

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Remdesivir- Potential Drug Repurposing Candidate for COVID-19

Mechanism of Action: RNA-dependent RNA polymerase (RdRp) inhibition

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Semantic Metadata Catalog for Metadata Management

Semantic Metadata Catalog for Metadata Management- A reference point within the Enterprise Data Lakes

Traditional techniques of Data Cataloging at a data storage level creates dispersed data silos across the enterprise. An intelligent automated Data Catalog linked to diverse and distributed data...

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Excelra COVID-19 Drug Repurposing Database

As the novel coronavirus pandemic continues to spread in an unyielding manner, COVID-19 has brought about unprecedented social, economic and health disruptions across the globe. Furthermore, there are currently no specific anti-viral drugs or vaccines to effectively treat or prevent COVID-19....

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Data in Health Care: How far have we come?

“What you measure will improve”- Aron Anderson

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Data Driven Drug Repurposing

"The industry is taking a more data-driven and strategic approach to Drug Repurposing."

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